"Biology for a brighter tomorrow"
Pioneering microbial products for food and pharma

"Nature provides opportunities, CUVIA creates solutions."image

Our Core Competencies

Strain Engineering

Wet lab and bioinformatics approaches to development of high yield microbial hosts for small and large molecule targets.

Process Development

Fermentation and downstream processing at scales ranging from lab to commercial.


Fermentation capacity and downstream unit operations for food and pharma grade products.


Meet specifications and quality requirements for food and pharma markets.

Meet the Leaders

Smita SHANKARimageFounder and CEO
"Smita's unique combination of scientific and business achievements inform the DNA of CUVIA. Her academic background includes doctoral and post doctoral work in transcription and epigenetic regulation. As an early employee of Impossible Foods, she led the R&D and biomanufacturing of heme, a high value ingredient of the Impossible Burger. With CUVIA, she is bringing to the world her convictions about the scope and scale that microbial products can achieve."
MARTIN HOYTimageChief Scientist
"Martin is a pioneering mind in molecular biology and industrial biotech. With a Ph.D. in molecular biology and extensive experience in yeast genetics and fungal biotech, he brings a visionary perspective to biological solutions. Known for his optimism and deep understanding of microbes, he sees boundless potential in biology's applications. As a compassionate problem-solver, he embodies CUVIA’s ethos: "Nature provides opportunities, CUVIA creates solutions." Embrace the genius behind nature's blueprints with Dr. Hoyt.!"
DAVID MELISimageVP of Bioprocess Development
"As Vice President of Bioprocess Development at CUVIA, David brings over 20 years of biotech expertise, having been instrumental at Amyris, Lygos, and Shiru. His specialization in fermentation technology spans various organisms, showcasing a successful history of scaling up operations. A recognized expert in his field, David's leadership aligns with CUVIA's mission to innovate and introduce groundbreaking products, exemplifying his dedication to expanding the frontiers of biotechnology."

Common Questions

What are microbial products?Microbes are unicellular organisms that are found in abundance in nature. They naturally produce many substances that are useful to us. Broadly, microbial products can be categorized as small molecules such as antibiotics, and large molecules such as food proteins and enzymes. These products have wide ranging applications across industries. In addition to these natural products, microbes can also be engineered to make molecules of plant and animal origin.
Can CUVIA make the product I need? CUVIA is building its product pipeline by listening to the market and building partnerships.
       -    Does your supply chain depend on complex biomolecules of microbial, plant, or animal origin?
       -    Are strain productivity, process optimization, tech transfer, and manufacturing costs proving to be barriers to commercialization?
CUVIA is uniquely equipped to develop, manufacture, and supply your molecule at industry competitive prices and quality. Please contact us.
What is biomanufacturing?Microbial products can be manufactured efficiently and safely at large scales by using a process called fermentation. This involves the use of bioreactors that create and maintain ideal conditions for the microbes to grow and carry out fermentation to make the product. Once fermentation is complete, downstream processes are used to separate and purify the product.
What is strain engineering?A strain is a genetic variant of a microbe that has a desirable property, such as the ability to make higher quantities of a certain molecule. Strains can be discovered or created. In nature, strains are naturally produced when microbes reproduce and adapt to various environmental pressures. We can screen for such natural variants to help us make microbial products. Using our knowledge of microbial genetics, we can also create such variants in the lab.